منابع مشابه
Intranasal midazolam vs rectal diazepam in acute childhood seizures.
One hundred eighty-eight seizure episodes in 46 children were randomly assigned to receive treatment with rectal diazepam and intranasal midazolam with doses of 0.3 mg/kg body weight and 0.2 mg/kg body weight, respectively. Efficacy of the drugs was assessed by drug administration time and seizure cessation time. Heart rate, blood pressure, respiratory rate, and oxygen saturation were measured ...
متن کاملThe Situation of Suppression Seizures with Diazepam by Rectal Administration in China
Seizures are a manifestation of temporary brain dysfunction caused by abnormal discharge of brain neurons, Repeated; sustained seizures can cause irreversible brain damage. Rapid, reasonable choice on anticonvulsant drugs, Fast and effective measures on panic stop, Suppress of abnormal discharge, Prevention of convulsions again, All of which has an irreplaceable role on brain injury and recover...
متن کاملDiazepam in the prophylaxis of lignocaine seizures.
Diazepam 0.05-0.25 mg/kg increased the dose of lignocaine required to cause seizures in Rhesus monkeys by 24-34%. Spontaneous ventilation was maintained adequately during lignocaine administration following diazepam treatment and no adverse cardiovascular effects occurred. Before the onset of lignocaine-induced seizures in non-treated animals, the animals appeared to be drowsy. However, prior t...
متن کاملRectal absorption of diazepam in epileptic children.
The absorption of diazepam after rectal administration was studied in children with epilepsy. When given as a solution, diazepam was rapidly absorbed and produced serum diazepam concentrations above 200 ng/ml within 10 minutes in most children. However, a commercial suppository formulation was absorbed slowly and cannot be recommended for urgent treatment of fits. There is a need in the UK for ...
متن کاملIntranasal midazolam vs rectal diazepam for the home treatment of acute seizures in pediatric patients with epilepsy.
OBJECTIVE To compare intranasal midazolam, using a Mucosal Atomization Device (IN-MMAD), with rectal diazepam (RD) for the home treatment of seizures in children with epilepsy. DESIGN Prospective randomized study. SETTING Patients' homes and a freestanding children's hospital that serves as a referral center for 5 states. PATIENTS A total of 358 pediatric patients who visited a pediatric ...
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ژورنال
عنوان ژورنال: Pediatric Neurology Briefs
سال: 1998
ISSN: 2166-6482,1043-3155
DOI: 10.15844/pedneurbriefs-12-12-7